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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM196897'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ALK tyrosine kinase receptor


(Homo sapiens (Human))
BDBM196897
PNG
(US9212192, 60)
Show SMILES NC(=O)c1c(Nc2ccc(cc2Cl)C2CCNCC2)nc(Cc2ccccc2Cl)n2cnnc12
Show InChI InChI=1S/C24H23Cl2N7O/c25-17-4-2-1-3-16(17)12-20-31-23(21(22(27)34)24-32-29-13-33(20)24)30-19-6-5-15(11-18(19)26)14-7-9-28-10-8-14/h1-6,11,13-14,28,30H,7-10,12H2,(H2,27,34)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1 -51.4n/an/an/an/an/a7.425



AbbVie Inc.

US Patent


Assay Description
ALK kinase assays were conducted with the indicated final concentrations unless otherwise specified. In 384 well black plates (Axygen), 8 ul of compo...


US Patent US9212192 (2015)


BindingDB Entry DOI: 10.7270/Q2D79971
More data for this
Ligand-Target Pair