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Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP Phosphoribosyltransferase' and Ligand = 'BDBM25319'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25319
PNG
(4,6-bis(benzylsulfanyl)pyrimidine-2,5-diamine | Ch...)
Show SMILES Nc1nc(SCc2ccccc2)c(N)c(SCc2ccccc2)n1
Show InChI InChI=1S/C18H18N4S2/c19-15-16(23-11-13-7-3-1-4-8-13)21-18(20)22-17(15)24-12-14-9-5-2-6-10-14/h1-10H,11-12,19H2,(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair