BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-binding cassette sub-family G member 2' and Ligand = 'BDBM50202240'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-binding cassette sub-family G member 2


(Homo sapiens (Human))
BDBM50202240
PNG
(CHEMBL3947261)
Show SMILES COc1ccc2[nH]cc(CCNC(=O)C(CC(C)C)NC(=O)c3cc(=O)c4c(OCc5ccc(Br)cc5)cccc4o3)c2c1
Show InChI InChI=1S/C34H34BrN3O6/c1-20(2)15-27(33(40)36-14-13-22-18-37-26-12-11-24(42-3)16-25(22)26)38-34(41)31-17-28(39)32-29(5-4-6-30(32)44-31)43-19-21-7-9-23(35)10-8-21/h4-12,16-18,20,27,37H,13-15,19H2,1-3H3,(H,36,40)(H,38,41)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/an/an/a 910n/an/an/an/a



Universit£ Lyon 1

Curated by ChEMBL


Assay Description
Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by flow cytometric analysis


Citation and Details
More data for this
Ligand-Target Pair