Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-binding cassette sub-family G member 2 (Homo sapiens (Human)) | BDBM50202240![]() (CHEMBL3947261) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 910 | n/a | n/a | n/a | n/a |
Universit£ Lyon 1 Curated by ChEMBL | Assay Description Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by flow cytometric analysis | Eur J Med Chem 122: 291-301 (2016) Article DOI: 10.1016/j.ejmech.2016.05.053 BindingDB Entry DOI: 10.7270/Q28K7C22 | |||||||||||
More data for this Ligand-Target Pair |