Found 3 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM195013' TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage
clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the
IonWorks ...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 10nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384
wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in
Poly-D...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 270nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384
wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in
Poly-D...More data for this Ligand-Target Pair
