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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Activated CDC42 kinase 1' and Ligand = 'BDBM50421293'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Activated CDC42 kinase 1


(Mus musculus)
BDBM50421293
PNG
(CHEMBL2087881)
Show SMILES CO[C@@H]1CC[C@H]1CNc1ncnc2[nH]c(c(-c3ccccc3)c12)-c1ccc(OCCN(C)C)cc1
Show InChI InChI=1S/C28H33N5O2/c1-33(2)15-16-35-22-12-9-20(10-13-22)26-24(19-7-5-4-6-8-19)25-27(30-18-31-28(25)32-26)29-17-21-11-14-23(21)34-3/h4-10,12-13,18,21,23H,11,14-17H2,1-3H3,(H2,29,30,31,32)/t21-,23+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of ACK1 in mouse C8 cells assessed as decrease in cell viability after 20 to 24 hrs


Bioorg Med Chem Lett 22: 6212-7 (2012)

More data for this
Ligand-Target Pair