BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Acyl coenzyme A:cholesterol acyltransferase 1' and Ligand = 'BDBM50450339'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450339
PNG
(CHEMBL45184)
Show SMILES CCCCCCN(CCCCCSc1nc2cc(OCC)ccc2s1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C27H35F2N3O2S2/c1-3-5-6-8-15-32(26(33)30-23-13-11-20(28)18-22(23)29)16-9-7-10-17-35-27-31-24-19-21(34-4-2)12-14-25(24)36-27/h11-14,18-19H,3-10,15-17H2,1-2H3,(H,30,33)
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

n/an/a 4.54E+3n/an/an/an/an/an/a



The DuPont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Bioorg Med Chem Lett 5: 167-72 (1995)


BindingDB Entry DOI: 10.7270/Q2Z03833
More data for this
Ligand-Target Pair