Found 65 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a' and Ligand = 'BDBM21190' 
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards human Adenosine A2a receptor expressed in HEK293 cells using 6 nM [3H]CGS-21680More data for this Ligand-Target Pair
3D Structure (crystal)TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:Binding affinity towards adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.302nMAssay Description:Antagonist activity at A2AR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.302nMAssay Description:Antagonist activity at A2AR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity against human Adenosine A2a receptor (hA2a)More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at human adenosine 2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant adenosine receptor A2aMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity to human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.900nMAssay Description:Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.900nMAssay Description:Inhibition of [3H]ZM-241385 binding to adenosine A2a receptor of rat brain tissueMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting meth...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]NECA from adenosine A2A receptor in Sprague-Dawley rat striatal membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I]Z241385 from human cloned adenosine A2A receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]NECA from Sprague-Dawley rat striatal membrane A2A adenosine receptor by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes after 1 hr by TopCount microplate scintillation count...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in Sprague-Dawley rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor by scintillation spectroscopyMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membrane incubated for 1 hr by microplate beta scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]ZM241385 from human recombinant A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by radioligand binding ...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]HZ241385 from human A2AAR expressed in HeLa cell membrane incubated for 30 mins by microbeta trilux scintillation counter analysi...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]4-(2-[7-amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol from human adenosine A2A receptor expressed ...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]ZM2421385 from adenosine A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement [3H]ZM241385 from adenosine A2A receptor in human HeLa cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]ZM241385 from human Adenosine A2A receptor expressed in HeLa cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]ZM241385 from human recombinant A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by radioligand binding ...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]ZM241385 from stabilized human adenosine receptor A2a expressed in HEK293 cells followed by receptor capturing on Biocore chips b...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Displacement of [3H]NECA from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Antagonist activity at rat A2A adenosine receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]SCH58261 from adenosine A2A receptor membrane (unknown origin) measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]NECA from rat adenosine A2A receptor expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]NECA from adenosine A2A receptor in Sprague-Dawley rat striatal membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of MRS5346 from C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pich...More data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]ZM-241385 from human cloned adenosine A2A receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 395nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as inhibition constant by surface plasmon resonance a...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 530nMAssay Description:Displacement [3H]-CGS-21,680 from Adenosine A2A receptor in rat striatal membrane.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 9.91E+8nMAssay Description:Displacement of [3H]ZM241385 from human A2AR expressed in CHO cells after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.91E+8nMAssay Description:Displacement of [3H]ZM241385 from human A2AR expressed in CHO cells after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
