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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Adrenergic receptor alpha-2' and Ligand = 'BDBM50070081'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha-2


(Homo sapiens (Human))
BDBM50070081
PNG
(CHEMBL3408032)
Show SMILES OCCNC1=NCc2ccccc2N1
Show InChI InChI=1S/C10H13N3O/c14-6-5-11-10-12-7-8-3-1-2-4-9(8)13-10/h1-4,14H,5-7H2,(H2,11,12,13)
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
550n/an/an/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Displacement of [3H]-RX-821002 from human alpha-2 adrenergic receptor in brain prefrontal cortex membrane by liquid scintillation spectrometry


J Med Chem 58: 963-77 (2015)

More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(Homo sapiens (Human))
BDBM50070081
PNG
(CHEMBL3408032)
Show SMILES OCCNC1=NCc2ccccc2N1
Show InChI InChI=1S/C10H13N3O/c14-6-5-11-10-12-7-8-3-1-2-4-9(8)13-10/h1-4,14H,5-7H2,(H2,11,12,13)
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.03E+4n/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Antagonist activity at human alpha-2 adrenergic receptor in brain prefrontal cortex membrane assessed as inhibition of UK14304-induced [35S]-GTPgamma...


J Med Chem 58: 963-77 (2015)

More data for this
Ligand-Target Pair