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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member C2' and Ligand = 'BDBM50385767'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldo-keto reductase family 1 member C2


(Homo sapiens (human))
BDBM50385767
PNG
(CHEMBL2043320)
Show SMILES COc1ccc(C(O)=O)c(Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C14H12ClNO3/c1-19-11-6-7-12(14(17)18)13(8-11)16-10-4-2-9(15)3-5-10/h2-8,16H,1H3,(H,17,18)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 290n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assay


J Med Chem 55: 2311-23 (2012)

More data for this
Ligand-Target Pair