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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor' and Ligand = 'BDBM50131676'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50131676
PNG
(CHEMBL262807)
Show SMILES C[C@@H]([C@@H](O)c1ccc(O)cc1)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H26N2O2/c1-16(20(24)18-7-9-19(23)10-8-18)22-13-11-21(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,20,23-24H,11-15H2,1H3/t16-,20+/m0/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.63E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Compound was tested for the binding affinity against Alpha-1 adrenergic receptor by using [3H]prazosin as radioligand


J Med Chem 34: 3085-90 (1991)


Article DOI: 10.1021/jm00114a018
BindingDB Entry DOI: 10.7270/Q2FN155W
More data for this
Ligand-Target Pair