BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1A adrenergic receptor' and Ligand = 'BDBM317585'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM317585
PNG
(US9624198, 10 | [4-(3,4-Dihydroisoquinolin-2(1H)-y...)
Show SMILES O=C(N1CCC(CC1)N1CCc2ccccc2C1)c1ccc(nc1)N1CC2(COC2)C1
Show InChI InChI=1S/C25H30N4O2/c30-24(20-5-6-23(26-13-20)29-15-25(16-29)17-31-18-25)27-11-8-22(9-12-27)28-10-7-19-3-1-2-4-21(19)14-28/h1-6,13,22H,7-12,14-18H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...


US Patent US9624198 (2017)

More data for this
Ligand-Target Pair