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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-2A adrenergic receptor' and Ligand = 'BDBM50377391'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50377391
PNG
(CHEMBL402388)
Show SMILES COc1cccc2C(CCc12)c1ncc[nH]1
Show InChI InChI=1S/C13H14N2O/c1-16-12-4-2-3-9-10(12)5-6-11(9)13-14-7-8-15-13/h2-4,7-8,11H,5-6H2,1H3,(H,14,15)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 27n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human cloned adrenergic alpha-2A receptor expressed in CHOK1 cells by beta-lactamase reporter gene assay


Bioorg Med Chem Lett 18: 2930-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.070
BindingDB Entry DOI: 10.7270/Q2VQ33KM
More data for this
Ligand-Target Pair