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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Alpha-2B adrenergic receptor' and Ligand = 'BDBM50002905'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-2B adrenergic receptor


(Homo sapiens (Human))
BDBM50002905
PNG
(CHEMBL373535)
Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1
Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
933n/an/an/an/an/an/an/an/a



Università degli Studi di Camerino

Curated by ChEMBL


Assay Description
Displacement of [3H]RX 821002 from human adrenergic alpha-2B receptor expressed in CHO cells


J Med Chem 50: 3964-8 (2007)

Checked by Author
Article DOI: 10.1021/jm061487a
BindingDB Entry DOI: 10.7270/Q2W095NP
More data for this
Ligand-Target Pair
Alpha-2B adrenergic receptor


(Homo sapiens (Human))
BDBM50002905
PNG
(CHEMBL373535)
Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1
Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.00E+3n/an/an/an/a



Università degli Studi di Camerino

Curated by ChEMBL


Assay Description
Agonistic potency at human adrenergic alpha-2B receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation


J Med Chem 50: 3964-8 (2007)

Checked by Author
Article DOI: 10.1021/jm061487a
BindingDB Entry DOI: 10.7270/Q2W095NP
More data for this
Ligand-Target Pair