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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amiloride-sensitive sodium channel alpha-subunit' and Ligand = 'BDBM50190489'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Amiloride-sensitive sodium channel alpha-subunit


(Homo sapiens (Human))
BDBM50190489
PNG
((4-{4-[N-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Show SMILES NC(NC(=O)c1nc(Cl)c(N)nc1N)=NCCCCc1ccc(OCCC(O)=O)cc1
Show InChI InChI=1S/C19H24ClN7O4/c20-15-17(22)26-16(21)14(25-15)18(30)27-19(23)24-9-2-1-3-11-4-6-12(7-5-11)31-10-8-13(28)29/h4-7H,1-3,8-10H2,(H,28,29)(H4,21,22,26)(H3,23,24,27,30)
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Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Parion Sciences Inc.

Curated by ChEMBL


Assay Description
Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assay


J Med Chem 49: 4098-115 (2006)


Article DOI: 10.1021/jm051134w
BindingDB Entry DOI: 10.7270/Q2FT8KNH
More data for this
Ligand-Target Pair