BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50144946'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50144946
PNG
(CHEMBL3763918)
Show SMILES CC(C)C[C@H](NC(=O)NCc1cccc(C)c1C)C(=O)NO
Show InChI InChI=1S/C16H25N3O3/c1-10(2)8-14(15(20)19-22)18-16(21)17-9-13-7-5-6-11(3)12(13)4/h5-7,10,14,22H,8-9H2,1-4H3,(H,19,20)(H2,17,18,21)/t14-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...


Eur J Med Chem 108: 21-7 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.021
BindingDB Entry DOI: 10.7270/Q2ZC84RN
More data for this
Ligand-Target Pair