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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50433060'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433060
PNG
(CHEMBL2376104)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C12H11ClN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433060
PNG
(CHEMBL2376104)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C12H11ClN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.58E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair