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Found 1 hit Enz. Inhib. hit(s) with Target = 'Anti-estrogen binding site (AEBS)' and Ligand = 'BDBM50396753'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Anti-estrogen binding site (AEBS)


(Homo sapiens (Human))
BDBM50396753
PNG
(CHEMBL2172349)
Show SMILES COc1cccc(CCN2CCc3cc(O)c(OC)cc3C2)c1
Show InChI InChI=1S/C19H23NO3/c1-22-17-5-3-4-14(10-17)6-8-20-9-7-15-11-18(21)19(23-2)12-16(15)13-20/h3-5,10-12,21H,6-9,13H2,1-2H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Martin-Luther-Universit£t Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...


J Med Chem 55: 7614-22 (2012)


Article DOI: 10.1021/jm3006096
BindingDB Entry DOI: 10.7270/Q2W95B9V
More data for this
Ligand-Target Pair