Affinity DataKi: 0.0880nMAssay Description:The inhibition constant (Ki) is the dissociation constant of an enzyme-inhibitor complex or a protein/small molecule complex, wherein the small molec...More data for this Ligand-Target Pair
Affinity DataKi: <1nM EC50: 8nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of Bcl-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to Bcl-2 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: <40nMAssay Description:Inhibition of BCL-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataKi: <40nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
Affinity DataKi: 283nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to N-terminus 6X His-tagged human Bcl2 expressed in Escherichia coli BL21 (DE3) cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of biotin-linker-Bax BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21 Star...More data for this Ligand-Target Pair
Affinity DataKd: 0.600nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair