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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Atrial natriuretic peptide receptor' and Ligand = 'BDBM50230981'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Atrial natriuretic peptide receptor


(Homo sapiens (Human))
BDBM50230981
PNG
(CHEMBL4070239)
Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC1N(C(N)=NC1=O)c1nc(NC(N)=N)nc(Nc2ccc(Nc3nc(NC(N)=N)nc(n3)N3C(C)C(=O)N=C3N)cc2)n1
Show InChI InChI=1S/C22H26N20O2.2C2HF3O2/c1-7-11(43)31-15(27)41(7)21-37-17(35-19(39-21)33-13(23)24)29-9-3-5-10(6-4-9)30-18-36-20(34-14(25)26)40-22(38-18)42-8(2)12(44)32-16(42)28;2*3-2(4,5)1(6)7/h3-8H,1-2H3,(H2,27,31,43)(H2,28,32,44)(H5,23,24,29,33,35,37,39)(H5,25,26,30,34,36,38,40);2*(H,6,7)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Asubio Pharma Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassay


Bioorg Med Chem 25: 1762-1769 (2017)


Article DOI: 10.1016/j.bmc.2017.01.026
More data for this
Ligand-Target Pair