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Found 4 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50044667'
TargetAurora kinase B(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50044667(CHEMBL3353362 | US10358436, Example A58 | US990780...)
Affinity DataIC50:  14nMAssay Description:Inhibition of AURKB (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50044667(CHEMBL3353362 | US10358436, Example A58 | US990780...)
Affinity DataIC50: <100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50044667(CHEMBL3353362 | US10358436, Example A58 | US990780...)
Affinity DataIC50: <100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50044667(CHEMBL3353362 | US10358436, Example A58 | US990780...)
Affinity DataIC50:  550nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails US Patent