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Found 5 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50273571'
TargetAurora kinase B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human Aurora kinase B/INCEP complex expressed in Escherichia coli BL21 (DE3) using gamma-[32P]ATP incubated for 1 hr by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)
Affinity DataIC50:  250nMAssay Description:Inhibition of aurora B kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human full-length His-tagged Aurora B expressed in baculovirus expression system using 5-FAM-LRRASLG-CONH2 as substrate pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Aurora-B immunoprecipitated from mitotic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)
Affinity DataIC50:  250nMAssay Description:Inhibition of aurora B kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed