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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50389244'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aurora kinase B


(Homo sapiens (Human))
BDBM50389244
PNG
(CHEMBL2063455)
Show SMILES Nc1n[nH]c2cccc(C(=O)Nc3cccc(CNC(=O)Nc4cccc(F)c4)c3)c12
Show InChI InChI=1S/C22H19FN6O2/c23-14-5-2-7-16(11-14)27-22(31)25-12-13-4-1-6-15(10-13)26-21(30)17-8-3-9-18-19(17)20(24)29-28-18/h1-11H,12H2,(H,26,30)(H3,24,28,29)(H2,25,27,31)
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Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Aurora B kinase by HTRF analysis in presence of 1 mM ATP


Bioorg Med Chem Lett 22: 4528-31 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.125
BindingDB Entry DOI: 10.7270/Q2T154RT
More data for this
Ligand-Target Pair