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Found 3 Enz. Inhib. hit(s) with Target = 'Baculoviral IAP repeat-containing protein 2' and Ligand = 'BDBM50078360'
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Ensemble Therapeutics

Curated by ChEMBL
LigandPNGBDBM50078360(CHEMBL3414728)
Affinity DataIC50:  5nMAssay Description:Inhibition of cIAP1 BIR2-3 (154 to 352 residues) (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Ensemble Therapeutics

Curated by ChEMBL
LigandPNGBDBM50078360(CHEMBL3414728)
Affinity DataIC50:  22nMAssay Description:Inhibition of XIAP BIR2-3 (125 to 356 residues) C202A/C213G mutant (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Ensemble Therapeutics

Curated by ChEMBL
LigandPNGBDBM50078360(CHEMBL3414728)
Affinity DataEC50:  30nMAssay Description:Inhibition of XIAP BIR2-3 (124 to 356 residues) C202A/C213G mutant (unknown origin) in human THP1 cells using fluoresceinated caspase-3 substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed