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Found 3 Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM139040'
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM139040(US8883784, 1)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM139040(US8883784, 1)
Affinity DataKi:  0.140nMAssay Description:Inhibition of F-Bak binding to GST-tagged BCL-XL (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM139040(US8883784, 1)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to N-terminal GST-tagged BCL-XL (unknown origin) assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed