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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta amyloid A4 protein' and Ligand = 'BDBM50178546'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta amyloid A4 protein


(Homo sapiens (human))
BDBM50178546
PNG
(4-(5-(4-(2-fluoroethylamino)phenyl)thiophen-2-yl)p...)
Show SMILES Oc1ccc(cc1)-c1ccc(s1)-c1ccc(NCCF)cc1
Show InChI InChI=1S/C18H16FNOS/c19-11-12-20-15-5-1-13(2-6-15)17-9-10-18(22-17)14-3-7-16(21)8-4-14/h1-10,20-21H,11-12H2
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
3.90n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Displacement of [125I]IMPY from beta amyloid plaque in brain homogenates


Bioorg Med Chem Lett 16: 1350-2 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.055
BindingDB Entry DOI: 10.7270/Q2HX1C83
More data for this
Ligand-Target Pair