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Found 7 Enz. Inhib. hit(s) with Target = 'Beta-3 adrenergic receptor' and Ligand = 'BDBM50146154'
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146154(KRP-114V | MK-4618 | Vibegron)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146154(KRP-114V | MK-4618 | Vibegron)
Affinity DataEC50:  86nMAssay Description:Agonist activity at rat beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Macaca mulatta)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146154(KRP-114V | MK-4618 | Vibegron)
Affinity DataEC50:  0.570nMAssay Description:Agonist activity at rhesus monkey beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146154(KRP-114V | MK-4618 | Vibegron)
Affinity DataEC50:  11nMAssay Description:Agonist activity at dog beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Macaca mulatta)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146154(KRP-114V | MK-4618 | Vibegron)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at rhesus monkey beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146154(KRP-114V | MK-4618 | Vibegron)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human adrenergic beta3 receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146154(KRP-114V | MK-4618 | Vibegron)
Affinity DataEC50:  122nMAssay Description:Agonist activity at rat beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed