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Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM116256'
TargetBeta-secretase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM116256(US10035794, Example 33 | US10683287, Example 33 | ...)
Affinity DataIC50:  820nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM116256(US10035794, Example 33 | US10683287, Example 33 | ...)
Affinity DataIC50:  820nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM116256(US10035794, Example 33 | US10683287, Example 33 | ...)
Affinity DataIC50:  820nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In DepthDetails US Patent