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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM123864'
Target
Beta-secretase 1
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM123864
(US8748418, 8)
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Affinity Data
IC50: 90nM
pH: 4.5
Assay Description:
The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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PC sid
Similars
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Details
US Patent
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