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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM136740'
Target
Beta-secretase 1
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM136740
(US8865911, 20e Isomer 1)
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Affinity Data
IC50: 1.10nM
pH: 9.2
Assay Description:
TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...
More data for this Ligand-Target Pair
Target Info
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Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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Ligand Info
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US Patent
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