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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM26505'
TargetBeta-secretase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM26505(BMCL181022 Compound 12 | N-[(2S,3R)-4-(benzylamino...)
Affinity DataIC50:  120nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM26505(BMCL181022 Compound 12 | N-[(2S,3R)-4-(benzylamino...)
Affinity DataIC50:  120nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed