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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50031616'
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50031616(CHEMBL3359761)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of BACE1 in HEK293 cells assessed as Abeta40 level after overnight incubation by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50031616(CHEMBL3359761)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of BACE1 (unknown origin) incubated for 60 mins prior to substrate addition measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed