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Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50393099'
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)
Affinity DataIC50:  2.20nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed