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Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM123875'
TargetBeta-secretase 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM123875(US8748418, 20)
Affinity DataIC50:  170nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In DepthDetails US Patent