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Found 6 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM25745'
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM25745(3-(1-methanesulfonylpiperidin-4-yl)-1-[4-(trifluor...)
Affinity DataIC50:  2nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM25745(3-(1-methanesulfonylpiperidin-4-yl)-1-[4-(trifluor...)
Affinity DataIC50:  2nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM25745(3-(1-methanesulfonylpiperidin-4-yl)-1-[4-(trifluor...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM25745(3-(1-methanesulfonylpiperidin-4-yl)-1-[4-(trifluor...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM25745(3-(1-methanesulfonylpiperidin-4-yl)-1-[4-(trifluor...)
Affinity DataIC50:  2.90nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Sus scrofa (Pig))
The Regents Of The University Of California

US Patent
LigandPNGBDBM25745(3-(1-methanesulfonylpiperidin-4-yl)-1-[4-(trifluor...)
Affinity DataIC50:  60nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent