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Found 3 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50300199'
TargetBile acid receptor(Homo sapiens (Human))
Universita Di Perugia

Curated by ChEMBL
LigandPNGBDBM50300199(6alpha-ethyl-23(S)-methyl-cholic acid | CHEMBL5676...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at FXR expressed in COS1 cells by cell-based bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Universita Di Perugia

Curated by ChEMBL
LigandPNGBDBM50300199(6alpha-ethyl-23(S)-methyl-cholic acid | CHEMBL5676...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at glutathione transferase-tagged human FXR-LBD using biotinylated Src-1 peptide incubated for 30 mins by recruitment coactivator as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Universita Di Perugia

Curated by ChEMBL
LigandPNGBDBM50300199(6alpha-ethyl-23(S)-methyl-cholic acid | CHEMBL5676...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at GST-tagged FXR-LBD using biotinylated-SRC-1 peptide as substrate preincubated with compound for 30 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed