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Found 3 Enz. Inhib. hit(s) with Target = 'Bile salt export pump' and Ligand = 'BDBM50237607'
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50237607(Ansamycin | CHEBI:45367 | LM-427 | Mycobutin | Rif...)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50237607(Ansamycin | CHEBI:45367 | LM-427 | Mycobutin | Rif...)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50237607(Ansamycin | CHEBI:45367 | LM-427 | Mycobutin | Rif...)
Affinity DataIC50:  2.67E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed