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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM50378979'
TargetC-C chemokine receptor type 4(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50378979(CHEMBL2011441)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at mouse CCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50378979(CHEMBL2011441)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50378979(CHEMBL2011441)
Affinity DataIC50:  200nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed