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Found 5 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM21284'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21284(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataKi:  0.210nM EC50:  9.5nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21284(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataKi:  0.214nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21284(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21284(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21284(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataEC50:  0.170nMAssay Description:Agonist activity at rat CB2 receptor assessed as inhibition of forskolin-induced cAMP production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed