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Found 4 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM50029959'
TargetCannabinoid receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50029959(CHEMBL3353442 | US11564928, Compound 61)
Affinity DataKi:  1.30nMAssay Description:HEK293DHEK293iHEK293sHEK293pHEK293lHEK293aHEK293cHEK293eHEK293mHEK293eHEK293nHEK293tHEK293 HEK293oHEK293fHEK293 HEK293[HEK2933HEK293HHEK293]HEK293CHE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50029959(CHEMBL3353442 | US11564928, Compound 61)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human recombinant CB2R expressed in U2OS cells assessed as inhibition of WIN-55212-induced beta-arrestin-GFP binding to recept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50029959(CHEMBL3353442 | US11564928, Compound 61)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human recombinant CB2R expressed in WIN-55212-stimulated U2OS cells assessed as increase in forskolin-mediated cAMP level afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50029959(CHEMBL3353442 | US11564928, Compound 61)
Affinity DataIC50: <100nMAssay Description:CB1R binding protocol involves the use of the same solution buffer used for both incubation and washing reaction (Tris-HCl, 50 mM; EDTA, 2.5 mM; MgCl...More data for this Ligand-Target Pair
In DepthDetails US Patent