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Found 10 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM26988'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nM ΔG°:  -8.17kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMpH: 8.3Assay Description:Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMAssay Description:Inhibition of human CA2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMAssay Description:Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26988(CHEMBL1644029 | CHEMBL1644698 | CHEMBL186200 | NO3...)
Affinity DataKi:  3.50E+7nMAssay Description:Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair