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Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM10337'
TargetCaspase-3(Homo sapiens (Human))
Washington University

LigandPNGBDBM10337((S)-1-(6-Fluoro-pyridin-2-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50:  9.10nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

LigandPNGBDBM10337((S)-1-(6-Fluoro-pyridin-2-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50:  9.12nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed