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Found 3 Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM19858'
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM19858(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
Affinity DataKi:  19nMAssay Description:Inhibitory constant against rabbit cathepsin K using Z-Phe-Arg-AMC substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM19858(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
Affinity DataIC50:  19nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM19858(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
Affinity DataIC50:  72nM EC50:  580nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed