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Found 5 Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM50095489'
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095489(CHEMBL275080 | N-(1-Cyano-pyrrolidin-3-yl)-benzene...)
Affinity DataKi:  90nMAssay Description:Inhibitory constant of the compound against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095489(CHEMBL275080 | N-(1-Cyano-pyrrolidin-3-yl)-benzene...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity tested against Human Cathepsin K receptor using gelatinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095489(CHEMBL275080 | N-(1-Cyano-pyrrolidin-3-yl)-benzene...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095489(CHEMBL275080 | N-(1-Cyano-pyrrolidin-3-yl)-benzene...)
Affinity DataIC50:  81nMAssay Description:Inhibitory constant of the compound against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095489(CHEMBL275080 | N-(1-Cyano-pyrrolidin-3-yl)-benzene...)
Affinity DataIC50:  750nMAssay Description:Inhibitory activity tested against Human Cathepsin K receptor using bone resorption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed