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Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Ligand = 'BDBM50314194'
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314194((+/-)-1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(3-(...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human cathepsin S by ADAM-28 substrate-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314194((+/-)-1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(3-(...)
Affinity DataIC50:  152nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10 fragment after 24 hrs by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed