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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Ligand = 'BDBM50322918'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin S


(Homo sapiens (Human))
BDBM50322918
PNG
(4-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)...)
Show SMILES OCCCOc1ccc(cc1C(F)(F)F)-c1ccnc(n1)C#N
Show InChI InChI=1S/C15H12F3N3O2/c16-15(17,18)11-8-10(2-3-13(11)23-7-1-6-22)12-4-5-20-14(9-19)21-12/h2-5,8,22H,1,6-7H2
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 4.5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S by fluorescence assay


Bioorg Med Chem Lett 20: 4507-10 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.043
BindingDB Entry DOI: 10.7270/Q2SJ1KTF
More data for this
Ligand-Target Pair