Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = 'Ceramide glucosyltransferase' and Ligand = 'BDBM18355'
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCeramide glucosyltransferase(Mus musculus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition mouse glucosylceramide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCeramide glucosyltransferase(Mus musculus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCeramide glucosyltransferase(Mus musculus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed