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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM9030'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholinesterase


(Homo sapiens (Human))
BDBM9030
PNG
((2E)-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-y...)
Show SMILES Clc1ccc2c(NCCCCCCNC(=O)\C=C\c3c[nH]c4ccccc34)c3CCCCc3nc2c1
Show InChI InChI=1S/C30H33ClN4O/c31-22-14-15-25-28(19-22)35-27-12-6-4-10-24(27)30(25)33-18-8-2-1-7-17-32-29(36)16-13-21-20-34-26-11-5-3-9-23(21)26/h3,5,9,11,13-16,19-20,34H,1-2,4,6-8,10,12,17-18H2,(H,32,36)(H,33,35)/b16-13+
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Similars

Article
PubMed
n/an/a 77n/an/an/an/an/an/a



Neuropharma



Assay Description
The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...


J Med Chem 48: 7223-33 (2005)


Article DOI: 10.1021/jm0503289
BindingDB Entry DOI: 10.7270/Q2QN64Z5
More data for this
Ligand-Target Pair