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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM144346'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chymase


(Homo sapiens (Human))
BDBM144346
PNG
(US8969348, 2-{4-[(1,4-Dimethyl-1H-indol-3-yl)methy...)
Show SMILES CCCC(C(O)=O)n1nc(Cc2cn(C)c3cccc(C)c23)c2ccccc2c1=O
Show InChI InChI=1S/C24H25N3O3/c1-4-8-21(24(29)30)27-23(28)18-11-6-5-10-17(18)19(25-27)13-16-14-26(3)20-12-7-9-15(2)22(16)20/h5-7,9-12,14,21H,4,8,13H2,1-3H3,(H,29,30)
PDB
MMDB

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Similars

US Patent
n/an/a 9n/an/an/an/a8.0n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....


US Patent US8969348 (2015)


BindingDB Entry DOI: 10.7270/Q2J38R8B
More data for this
Ligand-Target Pair