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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50101136'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chymase


(Homo sapiens (Human))
BDBM50101136
PNG
(1,3-Bis-benzo[1,3]dioxol-5-ylmethyl-[1,3]diazetidi...)
Show SMILES O=C1N(Cc2ccc3OCOc3c2)C(=O)N1Cc1ccc2OCOc2c1
Show InChI InChI=1S/C18H14N2O6/c21-17-19(7-11-1-3-13-15(5-11)25-9-23-13)18(22)20(17)8-12-2-4-14-16(6-12)26-10-24-14/h1-6H,7-10H2
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.850n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Compound was evaluated for its inhibitory activity against human Serine protease chymase


Bioorg Med Chem Lett 11: 1691-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00264-5
BindingDB Entry DOI: 10.7270/Q2V12421
More data for this
Ligand-Target Pair