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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation Factor VIII' and Ligand = 'BDBM59160'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59160
PNG
(6209549)
Show SMILES COc1cc(C=Nn2c(O)csc2=S)ccc1OCCOc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C23H26N2O4S2/c1-23(2,3)17-6-8-18(9-7-17)28-11-12-29-19-10-5-16(13-20(19)27-4)14-24-25-21(26)15-31-22(25)30/h5-10,13-15,26H,11-12H2,1-4H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.24E+4n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair